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Lymphoma presenting as severe left ventricular systolic dysfunction: a case report

Imran Hafeez1, Mohd S Alai1, Khurshid Iqbal1

  • 1Department of Cardilogy Shere-Kashmir-Institute of Medical Sciences (SKIMS) Soura, Srinagar, J&K, India 190011.

Oman Medical Journal
|June 18, 2014
PubMed

Insights

This rare case report details a patient with non-Hodgkin lymphoma presenting with heart failure and kidney involvement. The lymphoma infiltrated the heart muscle, causing severe left ventricular dysfunction, a unique clinical presentation.

Area of Science:

  • Cardiology
  • Oncology
  • Nephrology

Background:

  • Cardiac lymphoma is an exceptionally rare clinical finding.
  • Non-Hodgkin lymphoma (NHL) typically affects lymph nodes but can involve extranodal sites.

Observation:

  • A patient presented with new-onset heart failure and severe left ventricular systolic dysfunction.
  • Simultaneous bilateral kidney involvement was noted.
  • Diagnosis revealed lymphoma infiltrating the heart muscle as the cause of cardiac dysfunction.

Findings:

  • This case represents the first documented instance of non-Hodgkin lymphoma presenting primarily with cardiac infiltration leading to heart failure.
  • The simultaneous bilateral kidney involvement further highlights the unusual extranodal presentation.

Implications:

  • This case expands the understanding of extranodal lymphoma manifestations.
  • Highlights the importance of considering rare cardiac involvement in lymphoma patients presenting with heart failure.
  • Suggests the need for broader diagnostic considerations in atypical lymphoma presentations.

Keywords:
Heart failureLeft ventricular systolic dysfunctionLymphoma

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