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Updated: Apr 28, 2026

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Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat
Published on: April 18, 2020
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[Median nerve neuropathy after perilunate dislocation injuries]
M Mühldorfer-Fodor1, B Hohendorff1, A A Saalabian1
1Klinik für Handchirurgie, Rhön-Klinikum, Bad Neustadt a.d. Saale.
Summary
Median nerve neuropathy is common after perilunate dislocations, often persisting despite surgery. Early carpal tunnel release does not always prevent long-term nerve issues and poorer outcomes.
Area of Science:
- Orthopedic Surgery
- Neurology
- Traumatology
Background:
- Perilunate dislocations are severe wrist injuries.
- Median nerve involvement can complicate recovery.
- Surgical decompression is a common treatment.
Purpose of the Study:
- To determine the frequency and presentation of median nerve neuropathy after perilunate dislocations.
- To assess the impact of surgical decompression on neuropathy.
- To correlate neuropathy with clinical outcomes.
Main Methods:
- Retrospective study of 32 patients with perilunate dislocations.
- Follow-up averaged 65 months post-surgery.
- Electrophysiological testing and clinical outcome measures (DASH, pain, grip strength, Mayo score) were used.
Main Results:
- Median nerve neuropathy occurred in a significant number of patients.
- Neuropathy persisted in 6 patients despite carpal tunnel release.
- Patients with neuropathy experienced worse pain, grip strength, and functional scores.
Conclusions:
- Median nerve neuropathy is a frequent complication of perilunate dislocations.
- It often presents as a chronic lesion rather than acute compression.
- Carpal tunnel release may not prevent persistent neurological deficits.
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