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Updated: Apr 28, 2026
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
The bone-implant interface - nanoscale analysis of clinically retrieved dental implants
Furqan Ali Shah1, Bengt Nilson2, Rickard Brånemark3
1Department of Biomaterials, Sahlgrenska Academy at University of Gothenburg, Göteborg, Sweden; BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Göteborg, Sweden.
Abstract:
Evaluation of the fine structure of the bone-implant interface in humans is a prerequisite for a deepened understanding of structure-function relationships with nano-modified biomaterials. In this study, three clinically stable, yet retrieved, laser-modified dental implants were evaluated using histological and interface ultrastructural analyses. The cumulative results for all threads containing intact tissue showed remodeled Haversian bone with bone area and bone-implant contact in excess of 85% and 80%, respectively. Collagen fibrils, laid down parallel to the surface oxide layer, were mineralized by plate-like crystallites of stoichiometrically relevant (Ca/P ratios 1.30-1.67) bone-apatite. An overlap of titanium, oxygen, calcium and phosphorus signals indicated the gradual intermixing of bone-apatite and the nano-rough surface oxide. These results suggest that bone bonding to nano-textured titanium implant surfaces is promoted in human jaw-bone after functional loading.
From The Clinical Editor:
In this study, newly developed and laser-modified titanium dental implants demonstrate strong evidence for implant-osseo integration basen on the surface and chemical analysis of three clinically stable dental implants.
