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Hemophilic Pseudotumor: An Important Differential Diagnosis of an Intracranial Mass

Claire L Anderson1, Ofelia Alvarez, Gaurav Saigal

  • 1*Division of Pediatric Hematology-Oncology †Department of Radiology, University of Miami, Miami, FL.

Journal of Pediatric Hematology/Oncology
|June 20, 2014
PubMed

Insights

Hemophilic pseudotumor, a rare complication of hemophilia, can occur in the skull. Early recognition and factor VIII treatment are crucial for managing this condition in young patients.

Area of Science:

  • Hematology
  • Pediatrics
  • Medical Complications

Background:

  • Hemophilia A is a genetic bleeding disorder.
  • Hemophilic pseudotumors are rare but serious complications.
  • Cranial involvement presents unique challenges.

Observation:

  • A male toddler with moderate hemophilia A presented with a cranial hemophilic pseudotumor.
  • The patient had a history of hemophilia A.

Findings:

  • The cranial hemophilic pseudotumor was successfully managed with factor VIII infusions.
  • Literature review confirms factor VIII as a primary treatment modality.

Implications:

  • Early diagnosis of hemophilic pseudotumor is vital.
  • Avoidance of unnecessary procedures like biopsy is critical as it is contraindicated.
  • This case highlights the importance of recognizing rare hemophilia complications.

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