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Updated: Apr 28, 2026

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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
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Multiple primary acral melanomas in two young caucasian patients
Goretti Lacruz1, Isabel Cárdenas, Cristina Carrera
1Melanoma Unit, Dermatology Department, Hospital Clínic of Barcelona, Barcelona, Spain.
Summary
Multiple primary acral melanomas (AM) are rare in Caucasians. This study reports the first cases, highlighting the possibility of BRAF mutations in high-risk patients and emphasizing the need for thorough acral examinations.
Area of Science:
- Dermatology
- Oncology
- Genetics
Background:
- Acral melanoma (AM) is an understudied melanoma subtype.
- Typically diagnosed in individuals over 50, often BRAF wild-type.

