Related Experiment Video
Updated: Apr 28, 2026
Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Comparative evaluation of antibacterial activity of total-etch and self-etch adhesive systems: An ex vitro study
Swathi Amin1, Harish K Shetty1, Ravi K Varma2
1Department of Conservative Dentistry and Endodontics, Yenepoya University, Mangalore, Karnataka, India.
Aim:
The aim of this ex vivo study was to compare the antibacterial activity of total-etch and self-etch adhesive systems against Streptococcus mutans, Lactobacillus acidophilus, and Actinomyces viscosus through disk diffusion method.
Materials And Methods:
The antibacterial effects of Single Bond (SB) and Adper Prompt (AP) and aqueous solution of chlorhexidine 0.2% (positive control) were tested against standard strain of S. mutans, L. acidophilus, and A. viscosus using the disk diffusion method. The diameters of inhibition zones were measured in millimeters. Data was analyzed using Kruskal-Wallis test. Mann-Whitney U test was used for pairwise comparison.
Result:
Of all the materials tested, AP showed the maximum inhibitory action against S. mutans and L. acidophilus. Aqueous solution of chlorhexidine 0.2% showed the maximum inhibitory action against A. viscosus. Very minimal antibacterial effect was noted for SB.
Conclusion:
The antibacterial effects observed for the tested different dentin bonding systems may be related to the acidic nature of the materials.
