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Updated: Apr 28, 2026
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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
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Periodic menstruation-linked psychosis of adolescence.
International Journal of Psychiatry in Clinical Practice
|June 20, 2014
Summary
Periodic Menstruation-Linked Psychosis of Adolescence (PMLPA) is a distinct syndrome in adolescent girls, differing from other psychoses. It is highly treatable with specific therapies, unlike traditional antipsychotics.
Area of Science:
- Psychiatry
- Adolescent Medicine
- Neuroscience
Background:
- A specific psychosis affecting adolescent girls has been sporadically reported for over a century.
- The distinct nature and clinical significance of this syndrome have not been fully recognized.
Purpose of the Study:
- To review the literature on this psychosis.
- To present clinical experience with 11 affected patients.
- To highlight the specificity and treatability of Periodic Menstruation-Linked Psychosis of Adolescence (PMLPA).
Main Methods:
- Literature review.
- Clinical case series presentation of 11 patients.
Main Results:
- Periodic Menstruation-Linked Psychosis of Adolescence (PMLPA) presents a unique clinical picture.
- The syndrome is unresponsive to traditional antipsychotic medications.
- PMLPA appears to respond to different therapeutic regimens.
Conclusions:
- Periodic Menstruation-Linked Psychosis of Adolescence (PMLPA) is a distinct and specific syndrome.
- Recognition of PMLPA is clinically important due to its high treatability with specific therapies.
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