Related Experiment Video
Updated: Apr 28, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Periodic menstruation-linked psychosis of adolescence
Abstract:
Clinical reports of a psychosis with distinct presentation affecting adolescent girls have appeared sporadically over more than a century, but its specificity has not been fully recognized. The literature is briefly reviewed and our experience with 11 such patients is presented. Periodic Menstruation-Linked Psychosis of Adolescence (PMLPA) appears to have a clinical picture which differs from that of any other form of psychosis, and to respond to different therapeutic regimes being at the same time totally unresponsive to traditional antipsychotic drugs. This makes the syndrome distinct, specific and highly treatable and therefore its recognition is of considerable clinical importance.
Related Concept Videos
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Bipolar Disorder
Disorders of the Female Reproductive System
Mania and Antimanic Drugs: Overview
Signs of Puberty

