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Biofilms01:29

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Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
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Functionalizing a dentin bonding resin to become bioactive.

Tobias T Tauböck1, Matthias Zehnder1, Thomas Schweizer2

  • 1Department of Preventive Dentistry, Periodontology and Cariology, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.

Dental Materials : Official Publication of the Academy of Dental Materials
|June 21, 2014
PubMed
Summary
This summary is machine-generated.

Alkaline bioactive glass nanoparticles were incorporated into dental resins, enhancing their bioactivity and pH induction without compromising hardness. This functionalized resin shows promise for dental applications.

Keywords:
Bioactive fillerBioglassBis-GMA/TEGDMACalcium phosphateComposite materialMicrohardnessNanoparticles

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Area of Science:

  • Biomaterials Science
  • Dental Materials
  • Nanotechnology

Background:

  • Dental resin composites are widely used but can lack bioactive properties.
  • Incorporating functional nanoparticles offers a strategy to enhance dental materials.
  • Alkaline bioactive glasses show potential for remineralization and pH buffering.

Purpose of the Study:

  • To investigate the chemo-mechanical effects of adding alkaline bioactive glass nanoparticles to a light-curable dental resin.
  • To evaluate the impact of these nanoparticles on properties like viscosity, water uptake, pH, hardness, and degree of conversion.

Main Methods:

  • Bis-GMA/TEGDMA dental resin was infiltrated with up to 20 wt% of SiO2-Na2O-CaO-P2O5-Bi2O3 nanoparticles.
  • Evaluated viscosity, water uptake, pH, Knoop hardness, and degree of conversion after 21-day immersion in PBS.
  • Analyzed resin surfaces using SEM for calcium phosphate precipitate formation and Raman spectroscopy.

Main Results:

  • Viscosity increased with nanoparticle loading but remained within the range of flowable composites.
  • Water uptake and pH induction significantly increased with higher nanoparticle concentrations.
  • 20 wt% nanoparticles maintained microhardness and slightly increased the degree of conversion; Ca/P precipitates formed.

Conclusions:

  • Bis-GMA-based dental resins can be effectively functionalized with alkaline bioactive glass nanoparticles.
  • Incorporating 20 wt% of these nanoparticles yields a material with bioactive properties and comparable hardness to unfilled resin.
  • This approach offers a pathway to developing enhanced dental restorative materials.