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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Travelers with sickle cell disease
Shaina M Willen1, Courtney D Thornburg, Paul M Lantos
1Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.
Journal of Travel Medicine
|June 21, 2014
Summary
Individuals with sickle cell disease (SCD) face significant health risks when traveling, particularly to tropical regions. Comprehensive pre-travel counseling and preventative measures are crucial for safe journeys.
Area of Science:
- Medical Science
- Genetics
- Public Health
Background:
- Sickle cell disease (SCD) is a prevalent genetic disorder, most common in individuals of African ancestry.
- Travel preparedness for individuals with SCD requires specific attention due to heightened health risks.
Purpose of the Study:
- To review travel-related risks and preparedness for individuals with sickle cell disease.
- To synthesize available literature to guide healthcare providers in pre-travel counseling for SCD patients.
Main Methods:
- Literature search for studies on travel preparedness and complications in SCD patients.
- Inclusion of topics such as malaria, infections, vaccinations, dehydration, altitude, and air travel.
Main Results:
- Limited specific literature exists on travel risks for SCD patients.
- Medical complication rates during travel appear high for individuals with SCD.
- Data from indigenous populations in Africa may offer insights but have uncertain generalizability to travelers.
Conclusions:
- Travelers with SCD face substantial risks including malaria, infections, dehydration, and vaso-occlusive crises.
- Essential pre-travel components include risk counseling, preventative strategies, and illness contingency planning.
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