Related Experiment Video
Updated: Apr 27, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Basic techniques in endoscopic ultrasound-guided fine needle aspiration for solid lesions: Adverse events and
Larissa L Fujii1, Michael J Levy1
1Mayo Clinic, Division of Gastroenterology and Hepatology, 200 1 St. SW, Rochester, MN 55905, USA.
Endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) aids diagnosis but carries risks like perforation and bleeding. This review details potential adverse events and offers strategies to minimize them for safer EUS-FNA procedures.
Area of Science:
- Gastroenterology
- Endoscopic Imaging
- Interventional Endoscopy
Background:
- Endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) is a key diagnostic tool for intrathoracic and intraabdominal conditions.
- While generally safe and accurate, EUS-FNA involves unique risks beyond standard endoscopic procedures due to the echoendoscope's capabilities.
Purpose of the Study:
- To review the risks associated with EUS-guided FNA.
- To identify and discuss specific adverse events related to the echoendoscope and FNA of solid masses.
- To provide practical guidance for avoiding common complications.
Main Methods:
- Literature review of adverse events associated with EUS-guided FNA.
- Analysis of risks inherent to echoendoscope use and FNA techniques.
- Compilation of preventative strategies for common complications.
Main Results:
- EUS-FNA carries risks including perforation, infection, bleeding, pancreatitis, pancreatic/bile duct leaks, and tumor seeding.
- Specific risks are linked to the echoendoscope's properties and the FNA process itself.
- Adverse events, though low-risk, require careful consideration and management.
Conclusions:
- Understanding the specific risks of EUS-FNA is crucial for patient safety.
- Implementing preventative measures can significantly reduce the incidence of adverse events.
- This review offers valuable insights for clinicians performing EUS-FNA to enhance procedural safety.
Related Concept Videos
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures V: ERCP
Patient...

