Related Experiment Video
Updated: Apr 27, 2026

Novel Mini-open Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
Minimally invasive transforaminal lumbar interbody fusion with unilateral pedicle screw fixation: comparison between
Moo Sung Kang1, Jeong Yoon Park1, Kyung Hyun Kim1
1Department of Neurosurgery, Gangnam Severance Hospital, Spine and Spinal Cord Institute, Yonsei University College of Medicine 712, Eonju Ro Gangnam-gu, Seoul 135-720, Republic of Korea.
Abstract:
Minimally invasive surgery with a transforaminal lumbar interbody fusion (MIS TLIF) is an important minimally invasive fusion technique for the lumbar spine. Lumbar spine reoperation is challenging and is thought to have greater complication risks. The purpose of this study was to compare MIS TLIF with unilateral screw fixation perioperative results between primary and revision surgeries. This was a prospective study that included 46 patients who underwent MIS TLIF with unilateral pedicle screw. The patients were divided into two groups, primary and revision MIS TLIF, to compare perioperative results and complications. The two groups were similar in age, sex, and level of operation, and were not significantly different in the length of follow-up or clinical results. Although dural tears were more common with the revision group (primary 1; revision 4), operation time, blood loss, total perioperative complication, and fusion rates were not significantly different between the two groups. Both groups showed substantial improvements in VAS and ODI scores one year after surgical treatment. Revision MIS TLIF performed by an experienced surgeon does not necessarily increase the risk of perioperative complication compared with primary surgery. MIS TLIF with unilateral pedicle screw fixation is a valuable option for revision lumbar surgery.
Insights
Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) offers comparable outcomes for primary and revision surgeries. Experienced surgeons can perform revision MIS TLIF without significantly increasing perioperative complications.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
Background:
- Minimally invasive lumbar fusion techniques are crucial for spinal conditions.
- Reoperation for lumbar spine issues presents unique challenges and potential risks.
Purpose of the Study:
- To compare perioperative outcomes and complications of minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) with unilateral screw fixation between primary and revision surgeries.
Main Methods:
- A prospective study involving 46 patients undergoing MIS TLIF with unilateral pedicle screw fixation.
- Patients were divided into primary and revision surgery groups for comparative analysis.
Main Results:
- No significant differences in operation time, blood loss, overall complications, or fusion rates between primary and revision groups.
- Dural tears were more frequent in the revision group (4 vs. 1).
- Both groups demonstrated significant improvements in VAS and ODI scores at one year post-surgery.
Conclusions:
- Revision MIS TLIF, when performed by experienced surgeons, does not inherently elevate perioperative complication risks compared to primary surgery.
- MIS TLIF with unilateral pedicle screw fixation is a viable and effective option for revision lumbar spine surgery.

