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Updated: Apr 27, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[Blood pressure control in patient with chronic kidney disease]
1Service de néphrologie-immunologie clinique, hôpital Bretonneau EA 4245, université François-Rabelais, 2, boulevard Tonnellé, 37000 Tours, France.
Insights
Controlling high blood pressure is crucial for patients with kidney disease. Recent studies and clinical trials have updated target blood pressure goals, changing clinical practice and guidelines for managing renal function.
Area of Science:
- Nephrology
- Cardiovascular Medicine
- Epidemiology
Context:
- High blood pressure (hypertension) is a known risk factor for worsening kidney function in individuals with renal disease.
- Established guidelines have historically recommended specific blood pressure targets for these patients.
- Recent research, including randomized clinical trials, has prompted revisions to these targets.
Purpose:
- To review the historical evolution of blood pressure control strategies in renal disease.
- To analyze how recent clinical trial data has influenced current understanding and recommendations.
- To explain the impact of new evidence on clinical practice and guideline development.
Summary:
- Epidemiological data consistently links hypertension to renal function decline in kidney disease patients.
- Previous guidelines set defined blood pressure targets, but these are evolving.
- Newer trials necessitate a re-evaluation of optimal blood pressure management in renal disease.
Impact:
- Updated understanding of the relationship between blood pressure and renal outcomes.
- Revised clinical practice patterns for managing hypertension in renal disease.
- Modification of national and international guidelines for blood pressure targets in kidney patients.
Abstract:
Several epidemiological studies have indicated that high blood pressure is associated with deterioration of renal function in patients with renal disease. Target blood pressures in patients with renal diseases have been defined and proposed to the community in several national and international guidelines. However, some of these targets have been recently changed to take into account results of studies, including randomized clinical trials. The aim of this paper is to put into perspective the history of ideas regarding adequate blood pressure control in patients with renal disease in the light of these results, and explain how these trials have changed our perception, practice and guidelines.
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