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Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart
Published on: September 28, 2016
[Effects of chocolate consumption on physiology and cardiovascular diseases]
1CHU Pontchaillou, pôle TVM, centre de prévention cardiovasculaire et consultation de facteurs de risque, département de cardiologie, 2, rue Henri-le-Guilloux, 35033 Rennes cedex 9, France.
Abstract:
Cocoa has a high content in polyphenols, especially flavonols. Flavonols exert a favourable effect on endothelium-derived vasodilation via the stimulation of nitric oxide-synthase (NOS), the increased availability of l-arginine (NO donor) and the decreased degradation of NO. Cocoa may also have a beneficial effect via the decreased platelet aggregation, the decreased lipid oxidation and insulin resistance. These effects are associated with a modest decrease of blood pressure and a favourable trend towards a reduction in cardiovascular events and strokes.
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