Coexistence of papillary thyroid cancer and Hashimoto thyroiditis in children: report of 3 cases
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Updated: Oct 13, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Harumi Koibuchi1, Kiyoka Omoto2, Noriyoshi Fukushima1
1Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
Abstract:
This report documents 3 pediatric papillary thyroid carcinoma cases with associated Hashimoto thyroiditis. In all 3 cases, hypoechoic nodules accompanied by multiple echogenic spots were noted on sonography of the thyroid. Hashimoto thyroiditis was suspected on the basis of positive thyroid autoantibody test results and pathologic examinations of thyroidectomy specimens, which revealed chronic thyroiditis with lymphocytic infiltration as the background of papillary thyroid carcinoma development. The potential for papillary carcinoma development warrants close follow-up, and meticulous sonographic examinations must be performed in children with Hashimoto thyroiditis.
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