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Mooren's Ulcer in a Cornea Referral Practice in Korea
Dong Hyun Kim1, Mee Kum Kim1,2, Won Ryang Wee1,2
1a Department of Ophthalmology , Seoul National University Hospital, Seoul National University Hospital , Seoul , Korea and.
Purpose:
To investigate the clinical characteristics of patients with Mooren's ulcer in the Korean population, and to identify the risk factors that affect the therapeutic outcome.
Methods:
We reviewed the medical records of 33 eyes of 24 Korean patients who were referred to a cornea clinic and clinically diagnosed with Mooren's ulcer.
Results:
Despite intensive immunosuppression, corneal perforation occurred in 16 of 24 (66.7%) patients, which required tectonic graft. Age was significantly correlated with corneal perforation development: the age was 52.5 ± 21.8 years in patients with perforation and 70.2 ± 6.1 years in those without perforation (p = 0.036). Also, all 8 patients who were 55 years and younger had corneal perforation, while 8 of 16 patients older than 55 years developed perforation (p = 0.022). Other factors had no significant correlation with the occurrence of perforation.
Conclusions:
Young patients with Mooren's ulcer should be treated and carefully followed for high possibility of corneal perforation.
