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Patient-reported outcome measures for asthma: a systematic review
Allison Worth1, Victoria Hammersley1, Rebecca Knibb2
1Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.
NPJ Primary Care Respiratory Medicine
|June 27, 2014
Summary
This study identified validated patient-reported outcome measures (PROMs) for asthma, including the Asthma Quality of Life Questionnaire (AQLQ) and Pediatric Asthma Quality of Life Questionnaire. Further validation is needed for clinical practice use.
Area of Science:
- Clinical Medicine
- Health Outcomes Research
- Respiratory Medicine
Background:
- Patient-reported outcome measures (PROMs) assess treatment outcomes directly from patients or caregivers.
- There is growing international policy interest in utilizing PROMs to evaluate clinical care impact.
Purpose of the Study:
- To identify validated patient-reported outcome measures (PROMs) for asthma.
- To assess the suitability of these PROMs for clinical settings.
Main Methods:
- Systematic literature search of MEDLINE, EMBASE, and Web of Science databases (1990 onwards).
- Critical appraisal and narrative synthesis of identified PROMs.
- Identification of generic PROMs commonly used with asthma-specific instruments.
Main Results:
- Identified 68 PROMs for asthma; 13 met criteria for full appraisal.
- Validated PROMs with clinical potential include AQLQ and mini-AQLQ (adults), and Pediatric Asthma Quality of Life Questionnaire (children).
- Rhinasthma showed promise for assessing coexistent asthma and rhinitis.
Conclusions:
- Specific asthma PROMs demonstrate potential for clinical application.
- Further research is required to confirm their fitness-for-purpose in clinical practice.
- Ensuring validation, acceptability, and meaningful outcomes is crucial for clinical implementation.
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