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Updated: Apr 27, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Catheter-directed clot fragmentation using the Cleaner™ device in a patient presenting with massive pulmonary
I Barjaktarevic1, O Friedman1, C Ishak2
1Division of Pulmonary and Critical Care Medicine, New York Presbyterian Hospital, Weill Cornell Medical College, New York, USA.
Abstract:
Massive pulmonary embolism not amenable to systemic thrombolysis is a therapeutic challenge. Catheter directed clot fragmentation and thrombolysis have been efficacious in this setting. We describe successfully treating a massive pulmonary embolism with catheter-directed thrombolysis and clot fragmentation using local tPA, aspiration, and the Cleaner™ device in a patient with an absolute contraindication to systemic thrombolysis.
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