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Immunoglobulin G subclass deficiency and susceptibility to pyogenic infections in patients with AIDS-related complex
J M Parkin1, M Helbert, C L Hughes
1Department of Immunology, St Mary's Hospital and Medical School, London, UK.
AIDS (London, England)
|January 1, 1989
Abstract:
Total immunoglobulin (Ig) and IgG subclass levels were measured in 72 patients with AIDS or AIDS-related complex (ARC). IgG2 subclass levels were found to be significantly decreased in the AIDS/ARC patients with pyogenic infections compared with both similar individuals without bacterial disease and the HIV-negative control group.