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Updated: Jan 23, 2026

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
Published on: April 28, 2023
Imaging biomarkers or biomarker imaging?
Markus Mitterhauser1, Wolfgang Wadsak2
1Radiochemistry and Biomarker Development Unit, Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, A-1090 Vienna, Austria. markus.mitterhauser@meduniwien.ac.at.
Abstract:
Since biomarker imaging is traditionally understood as imaging of molecular probes, we highly recommend to avoid any confusion with the previously defined term "imaging biomarkers" and, therefore, only use "molecular probe imaging (MPI)" in that context. Molecular probes (MPs) comprise all kinds of molecules administered to an organism which inherently carry a signalling moiety. This review highlights the basic concepts and differences of molecular probe imaging using specific biomarkers. In particular, PET radiopharmaceuticals are discussed in more detail. Specific radiochemical and radiopharmacological aspects as well as some legal issues are presented.
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