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Updated: Apr 27, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Giant rectal gastrointestinal stromal tumours: a diagnostic and therapeutic challenge
L S Alder1, G Elver2, F J Foo3
1Department of Surgery, Great Western NHS Trust, Swindon, UK Royal Blackburn Hospital, East Lancashire Hospital Trust, Blackburn, UK luluald@hotmail.com.
Abstract:
Gastrointestinal stromal tumour (GIST are the most common mesenchymal tumours; however, rectal GISTs account for <5%. In the pelvis they represent a diagnostic challenge with giant GISTs likely to be malignant. They may present with urological, gynaecological or rectal symptoms. Sphincter-preserving surgery can be aided by neoadjuvant therapy. We present an uncommon case of giant rectal GIST masquerading as acute urinary retention.

