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Wireless EWOD/DEP chips powered and controlled through LC circuits and frequency modulation.

Sung-Yueh Wu1, Wensyang Hsu

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This study introduces novel wireless electroosmotic flow (EOF) and dielectrophoresis (DEP) chips. These chips enable precise droplet manipulation and liquid pumping using frequency-tuned resonant circuits for wireless control.

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Area of Science:

  • Microfluidics
  • Electrowetting
  • Dielectrophoresis
  • Wireless Power Transfer

Background:

  • Traditional microfluidic devices often require complex wired connections for actuation.
  • Existing wireless methods for droplet manipulation typically use one-to-one transmitter-receiver coupling, limiting scalability.
  • There is a need for efficient wireless control systems for lab-on-a-chip applications.

Purpose of the Study:

  • To develop and demonstrate a novel wireless electroosmotic flow (EOF) and dielectrophoresis (DEP) chip.
  • To enable one-to-many wireless control of microfluidic operations using frequency-selective resonant circuits.
  • To showcase the capabilities of the proposed system for droplet manipulation and liquid pumping.

Main Methods:

  • Fabrication of wireless EWOD/DEP chips with multiple receiving LC circuits, each tuned to a unique resonant frequency.
  • Utilizing a single transmitter to wirelessly power and control multiple receivers through inductive coupling.
  • Modulating the input frequency to selectively activate EWOD/DEP electrodes for droplet and liquid manipulation.
  • Demonstrating droplet transport, splitting, and merging, as well as wireless liquid pumping using DEP.

Main Results:

  • Successful wireless control and actuation of EWOD/DEP electrodes using frequency-tuned LC circuits.
  • Demonstrated droplet manipulation (transport, splitting, merging) with 5 receivers at 1210-1920 Hz.
  • Achieved wireless liquid pumping with multiple electrodes (5 receivers) at 51.2-76.1 kHz.
  • Showcased continuous liquid pumping and distance tuning on a meandered electrode via frequency modulation.

Conclusions:

  • The proposed one-to-many wireless EWOD/DEP system offers a scalable and efficient solution for microfluidic control.
  • Frequency-selective resonance provides a robust mechanism for selective and sequential electrode activation.
  • This technology has significant potential for applications in automated biological assays, point-of-care diagnostics, and lab-on-a-chip systems.