[The influence of ultraviolet irradiation on sandblasted and acid-etching surface adsorbing human fibronectin]
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Updated: Apr 27, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
Published on: January 29, 2022
Shaobing Li1, Xueyang Zhang2, Jia Ni
1Department of Periodontics and Implantology,Guangdong Provincial Stomatological Hospital & The Affiliated Stomatological Hospital of Southern Medical University, Guangzhou 510280, China.
Objective:
To study the influence of ultraviolet (UV) irradiation on physical and chemical properties of sandblasted and acid-etched (SA) titanium surface and their ability to adsorb human fibronectin (HFn).
Methods:
SA and UV-SA surfaces were separately prepared. Surface morphology, roughness, elemental composition, wettability and HFn adsorption assay were performed for comparative analysis of these two surfaces.
Results:
SA and UV-SA surface had a similar morphology with multi-holes, and average roughness. UV-SA surface had a lower C content (22.83%) and higher O content (51.20%) and presented hydrophilicity, while SA surface showed hydrophobicity. But the quantity of adsorbed HFn on SA surface at 10 min assay point [(0.41 ± 0.07) µg] was statistically higher than that on UV-SA surface [(0.26 ± 0.08) µg](P = 0.007).
Conclusions:
UV irradiation would not change the morphology and roughness of SA surface. However, it could reduce the hydrocarbon and increase the hydroxyl groups, and the absorption of HFn on UV-SA surface at 10 min assay point was statistically lower than that on SA surface. Therefore, the in-vitro bioactivity of UV-SA surface was not as good as that of SA surface.

