Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ribosome Profiling02:24

Ribosome Profiling

3.2K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.2K
Proteomics01:33

Proteomics

7.5K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Instrumentation Failure After Posterior Vertebral Column Resection in Adult Spinal Deformity.

Spine·2016
Same author

Nanodrug-Mediated Thermotherapy of Cancer Stem-Like Cells.

Journal of nanoscience and nanotechnology·2016
Same author

Irisin exerts dual effects on browning and adipogenesis of human white adipocytes.

American journal of physiology. Endocrinology and metabolism·2016
Same author

Asymmetric Supercapacitor Based on Porous N-doped Carbon Derived from Pomelo Peel and NiO Arrays.

ACS applied materials & interfaces·2016
Same author

Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line.

Journal of the neurological sciences·2016
Same author

[Anatomic characteristics of the vessels in the spermatic cord of the varicocele patient: A laparoscopic study].

Zhonghua nan ke xue = National journal of andrology·2016
Same journal

Cerebral organoids and organoid intelligence: ethical challenges and governance pathway.

Frontiers of medicine·2025
Same journal

Immune cells in diabetic wound repair: the key to better wound management.

Frontiers of medicine·2025
Same journal

LMWH prophylaxis in pregnancy outcomes of women with suspected protein S deficiency: a retrospective case-control study.

Frontiers of medicine·2025
Same journal

Roles of different methylation modifications in cardiovascular disease.

Frontiers of medicine·2025
Same journal

Prognostic utility of baseline ASCL1/INSM1 expression and neutrophil-lymphocyte ratio in unresectable SCLC treated with first-line chemoimmunotherapy with or without radiotherapy.

Frontiers of medicine·2025
Same journal

"Zero-distance" photocrosslinking: a paradigm shift in probing DNA-protein dynamics.

Frontiers of medicine·2025
See all related articles

Related Experiment Video

Updated: Apr 27, 2026

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
09:34

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Published on: October 25, 2018

6.0K

Transcriptomics and proteomics in stem cell research.

Hai Wang1, Qian Zhang, Xiangdong Fang

  • 1CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.

Frontiers of Medicine
|June 29, 2014
PubMed
Summary
This summary is machine-generated.

Stem cell self-renewal and differentiation are key life science topics. Integrative multi-omics analysis, combining transcriptomics and proteomics, offers a promising systemic approach to understanding these complex stem cell processes.

More Related Videos

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling
08:38

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling

Published on: May 22, 2021

4.8K
Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR
09:03

Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR

Published on: May 29, 2014

11.1K

Related Experiment Videos

Last Updated: Apr 27, 2026

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
09:34

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Published on: October 25, 2018

6.0K
Analysis of Translation in the Developing Mouse Brain using Polysome Profiling
08:38

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling

Published on: May 22, 2021

4.8K
Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR
09:03

Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR

Published on: May 29, 2014

11.1K

Area of Science:

  • Life Sciences
  • Stem Cell Biology
  • Molecular Biology

Background:

  • Stem cells possess unique self-renewal and differentiation capabilities.
  • Understanding the molecular regulation of stem cell behavior is crucial.
  • Current research extensively examines stem cell self-renewal, proliferation, and differentiation.

Purpose of the Study:

  • To review and synthesize existing knowledge on stem cell processes.
  • To highlight the importance of integrative multi-omics analysis.
  • To emphasize the potential of systemic methodologies in stem cell research.

Main Methods:

  • Literature review of published studies.
  • Analysis of transcriptomic and proteomic data.
  • Focus on characterization of stem cell processes.

Main Results:

  • Stem cell self-renewal and differentiation are complex, regulated processes.
  • Multi-omics integrative analysis provides a systemic view.
  • Transcriptomic and proteomic data are key to understanding these mechanisms.

Conclusions:

  • A systemic approach is essential for comprehensive understanding of stem cell biology.
  • Integrative multi-omics analysis strengthens stem cell research.
  • Advancing stem cell knowledge promotes clinical applications.