Double-blind evaluation of the effect of acute amantadine on cocaine craving
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F H Gawin1, C Morgan, T R Kosten
1Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519.
Psychopharmacology
|January 1, 1989
Abstract:
Single doses of amantadine hydrochloride and placebo were administered in a double-blind cross-over design on separate days to ten actively craving cocaine abusers in treatment. Pharmacological treatment did influence cocaine craving, but amantadine was less effective than placebo.