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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
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Staphylococcus caprae bone and joint infections: a re-emerging infection?
1Centre de Référence des Infections Ostéo-Articulaires interrégional Sud-Méditerranée, Service des Maladies Infectieuses, CHU de la Conception, Marseille, France; Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France.
Summary
Staphylococcus caprae bone and joint infections (BJIs) are under-reported emerging hospital-acquired infections, often linked to orthopaedic devices. Removal of these devices is crucial for successful treatment and preventing relapses.
Area of Science:
- Infectious Diseases
- Orthopaedics
- Microbiology
Background:
- Staphylococcus caprae is increasingly recognized as a human pathogen.
- Bone and joint infections (BJIs) caused by S. caprae are under-reported.
- Orthopaedic device-related infections are a significant concern in healthcare settings.
Purpose of the Study:
- To report and review cases of Staphylococcus caprae bone and joint infections (BJIs).
- To identify risk factors, clinical characteristics, and treatment outcomes for S. caprae BJIs.
- To highlight the association between S. caprae BJIs and orthopaedic devices.
Main Methods:
- Retrospective case series of 25 S. caprae BJIs.
- Literature review of 31 published cases.
- Utilized molecular techniques and MALDI-TOF MS for bacterial identification.
Main Results:
- S. caprae BJIs predominantly affect the lower limbs (96%) and are frequently associated with orthopaedic devices (88%).
- Joint prosthesis infections (JPIs) and internal osteosynthesis device infections (I-ODIs) constitute the majority of cases.
- Polymicrobial infections were noted in 40% of cases, particularly associated with I-ODIs and malignancy history.
Conclusions:
- Staphylococcus caprae BJI is an underestimated, emerging hospital-acquired infection.
- Infections involving orthopaedic devices require device removal for effective management.
- Surgical intervention, particularly device removal, is critical for preventing relapses in S. caprae BJIs.
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