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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

825
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

921
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
921
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

627
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
627

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Related Experiment Video

Updated: Apr 27, 2026

Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

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The marginal kidney donor.

Umberto Maggiore1, Paolo Cravedi

  • 1aTrapianti Rene-Pancreas (U.O.C. Nefrologia), Azienda Ospedaliero-Universitaria di Parma, Parma, Italy bRenal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Current Opinion in Organ Transplantation
|July 1, 2014
PubMed
Summary
This summary is machine-generated.

Maximizing the use of marginal kidneys involves strategies like utilizing donors after circulatory death and advanced-age living donors. Further research is needed to refine criteria for marginal living kidney donors.

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Last Updated: Apr 27, 2026

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Area of Science:

  • Nephrology
  • Transplantation Immunology
  • Organ Procurement

Background:

  • Global organ shortage necessitates expanding donor criteria.
  • Maximizing utilization of marginal kidneys is crucial for meeting demand.
  • Previous criteria excluded donors now considered viable.

Purpose of the Study:

  • To review recent advances in strategies for using marginal kidney allografts.
  • To summarize methods for optimizing procurement and allocation of marginal kidneys.
  • To assess outcomes without compromising patient results.

Main Methods:

  • Review of current literature on marginal kidney donation and transplantation.
  • Analysis of strategies for donor selection and organ preservation.
  • Evaluation of outcomes associated with different donor types and preservation techniques.

Main Results:

  • Donors after circulatory death are increasingly utilized.
  • Normothermic ex-vivo and postmortem perfusion show promise for graft preservation.
  • Dual-kidney transplantation is a viable but potentially underutilized approach.
  • Pretransplant biopsy remains the gold standard for organ quality assessment.
  • Use of older living donors is supported; use of young donors with minor abnormalities requires further study.

Conclusions:

  • Significant progress in evaluating, recovering, and allocating marginal kidney donors.
  • Further research is essential, particularly for marginal living kidney donors.
  • Optimizing marginal kidney utilization can improve transplant rates and patient outcomes.