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Pathophysiology of empty nose syndrome
Jeanie Sozansky1, Steven M Houser
1Northeast Ohio Medical University, Rootstown, Ohio.
The Laryngoscope
|July 1, 2014
Summary
Empty Nose Syndrome (ENS) is not fully explained by anatomy alone. Aberrations in neurosensory systems after surgery may cause abnormal nasal airflow sensations in ENS patients.
Area of Science:
- Otolaryngology
- Rhinology
- Neuroscience
Background:
- Empty Nose Syndrome (ENS) is a complex condition characterized by paradoxical symptoms of nasal obstruction despite objective evidence of nasal patency.
- Current understanding of ENS often relies heavily on anatomical factors, which may not fully account for the subjective sensory experiences reported by patients.
Purpose of the Study:
- To synthesize current knowledge regarding nasal airflow sensation and its relationship to the pathophysiology of Empty Nose Syndrome.
- To propose an evidence-based hypothesis for the development and symptoms of ENS, integrating sensory and neural mechanisms.
Main Methods:
- A comprehensive literature search was conducted using PubMed.
- The review focused on studies related to the measurement of nasal patency, the mechanisms of nasal airflow sensory perception, and the clinical presentation of ENS.
Main Results:
- Anatomical analysis alone is insufficient to explain the symptoms of ENS.
- Advances in understanding subjective nasal sensation and nasal airflow dynamics have been made.
- Improper neural healing following surgical interventions can lead to neurosensory aberrations, potentially causing the abnormal sensations experienced in ENS.
Conclusions:
- An evidence-based hypothesis for the development and symptoms of ENS is presented.
- The hypothesis emphasizes the role of neurosensory system dysfunction in ENS, moving beyond purely anatomical explanations.
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