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Updated: Apr 27, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Is 18F-flutemetamol PET/CT able to reveal cardiac amyloidosis?
Renaud Lhommel1, Christine Sempoux, Adrian Ivanoiu
1From the Departments of *Nuclear Medicine, †Pathology, ‡Neurology, §Hematology, and ¶Cardiology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium.
Abstract:
We report here the case of a 56-year-old man with well-documented cardiac light chain amyloidosis successfully imaged with F-flutemetamol PET/CT in 2011. A matched pair healthy volunteer was imaged in the same conditions, and no specific heart uptake could be detected. The present report suggests the potential benefit of this new pharmaceutical in this indication, as it has been recently reported for C-Pittsburgh compound B, but with the main advantage to benefit from the more practical half-life of F. Further prospective trials would, however, be required to define the potential impact of F-flutemetamol PET/CT in cardiac amyloidosis.
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