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Updated: Apr 27, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Hollow sphere formation from a three-dimensional structure composed of an adamantane-based cage
Masahide Tominaga1, Kazuaki Ohara, Kentaro Yamaguchi
1Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University , 1314-1 Shido, Sanuki Kagawa 769-2193, Japan.
Abstract:
An adamantane-based cage with a three-dimensional (3D) framework was synthesized by the copper-mediated acetylene coupling reaction, in which two 1,3,5-triethynyladamantane units were linked by phenyldiacetylenic bridges possessing ester groups. X-ray crystallography revealed that the cage has an internal space and accommodates a solvent molecule, which afforded molecular networks through CH/O interactions between cage molecules. Furthermore, the cage containing six ester groups spontaneously self-assembled into hollow spherical aggregates with an average diameter of 230 nm in a mixed solvent.
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