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Updated: Apr 27, 2026
16:31
Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
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Optimal fluid resuscitation in trauma: type, timing, and total
Marcie Feinman1, Bryan A Cotton, Elliott R Haut
1aDepartment of Surgery, Johns Hopkins Medicine, Baltimore, Maryland bDepartment of Surgery and The Center for Translational Injury Research, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Current Opinion in Critical Care
|July 1, 2014
Summary
For trauma patients, limit crystalloid fluids and favor blood products for better outcomes. Resuscitation strategies should shift from damage control to targeted methods once bleeding is controlled.
Area of Science:
- Trauma Resuscitation
- Intravenous Fluid Therapy
- Hemorrhagic Shock Management
Background:
- Optimal intravenous fluid strategies for trauma patients remain debated.
- Early fluid administration can negatively impact outcomes.
Purpose of the Study:
- Review current literature on optimal fluid type and volume for trauma patients.
- Discuss damage control resuscitation and targeted resuscitation strategies.
- Incorporate new technologies in resuscitation guidance.
Main Methods:
- Literature review of recent studies on trauma fluid resuscitation.
- Analysis of prehospital, emergency department, and ICU management.
- Evaluation of damage control resuscitation principles.
Main Results:
- Prehospital crystalloid use is linked to worse outcomes.
- Damage control resuscitation favors blood products over large-volume crystalloids.
- Thrombelastography and new technologies aid in guiding resuscitation.
Conclusions:
- Limit crystalloids; prioritize blood components in acute trauma resuscitation.
- Transition from damage control to targeted resuscitation post-hemostasis.
- Utilize global and regional perfusion markers for optimal resuscitation.
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