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Published on: August 15, 2018
D-lactic acidosis in neonatal ruminants
Ingrid Lorenz1, Arcangelo Gentile2
1UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Abstract:
Metabolic acidosis in calves with neonatal diarrhea was believed to be mainly caused by the loss of bicarbonate via the intestines or the formation of L-lactate during anaerobic glycolysis after tissue hypoperfusion in dehydrated calves. Because D-lactate was not considered to be of interest in human or veterinary medicine, routine diagnostic methods targeted the detection of L-lactate only. The development of stereospecific assays for the measurement of D-lactate facilitated research. This article summarizes the available information on D-lactic metabolic acidosis in neonatal ruminants.
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