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Updated: Apr 27, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Time to treatment-door-to-balloon time is not everything
1Department of cardiology B, Aarhus University Hospital in Skejby, Skejby, Denmark, chriterk@rm.dk.
Insights
Accurate measurement of healthcare quality for ST-elevation myocardial infarction (STEMI) requires clear definitions of performance metrics. This study highlights the confusion around door-to-balloon time and system delay, advocating for standardized definitions.
Area of Science:
- Cardiology
- Healthcare Quality Improvement
- Health Systems Research
Background:
- International guidelines recommend performance measures to assess STEMI care quality.
- Door-to-balloon (D2B) time and system delay are key metrics for primary percutaneous coronary intervention (PPCI).
- Current definitions lack clarity, leading to confusion in reperfusion strategy assessment.
Purpose of the Study:
- To call for consensus on objective performance measures for STEMI management.
- To clarify definitions of D2B time and system delay.
- To demonstrate the inadequacy of focusing solely on D2B time.
Main Methods:
- Literature review and critical analysis of existing performance measures for STEMI.
- Examination of definitions for D2B time and system delay.
- Discussion of the implications for reperfusion strategy.
Main Results:
- Significant confusion exists regarding the precise definitions of D2B time and system delay.
- System delay and PCI-related delay are frequently used interchangeably, exacerbating definitional ambiguity.
- Focusing exclusively on D2B time is insufficient for comprehensive quality assessment.
Conclusions:
- There is a critical need for standardized, objective performance measures in STEMI care.
- Clearer definitions of D2B time and system delay are essential for accurate quality monitoring.
- A consensus on performance measure definitions will improve STEMI system of care evaluation and patient outcomes.
Abstract:
International guidelines for the management of patients with ST-elevation myocardial infarction (STEMI) recommend various performance measures to monitor the quality of STEMI systems of care. Door-to-balloon (D2B) time (arrival at hospital to percutaneous coronary intervention, PCI) and overall health care system delay (first medical contact to reperfusion) are acknowledged as valuable performance measures when treating patients with primary percutaneous coronary intervention (PPCI). However, there is confusion regarding the exact definition of these performance measures, and moreover system delay and PCI-related delay (the extra delay acceptable to perform PPCI instead of fibrinolysis) are often used synonymously, which add confusion when considering reperfusion strategy. The present paper calls for a consensus regarding the use and definition of objective performance measures when treating patients with STEMI, and exemplifies why it is insufficient just to focus on D2B time.
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