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Published on: November 3, 2010
Molecular motors as drug delivery vehicles
Richard N Cohen1, Mark J Rashkin2, Xin Wen2
1Joint Graduate Group in Bioengineering, UC San Francisco/UC Berkeley, 513 Parnassus Avenue Box 0446, San Francisco, CA 94143, USA.
Abstract:
Molecular motors that make up the intracellular transport system are akin to subway cars and trains that ply the rails of cities. The inner workings of these extraordinarily complicated systems are being explicated at the atomic level at a phenomenal rate, and it is becoming apparent that we are on the verge of bioengineering these motors for specialized applications. These systems might be the key to yet unsolved biomedical applications that include non-viral gene therapy and interneuron drug delivery.:
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