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Updated: Apr 27, 2026

Functional Characterization of Carboxylesterases in Insecticide Resistant House Flies, Musca Domestica
Published on: August 23, 2018
[Fe4L6](8+) cages: encapsulation and catalytic degradation of an insecticide
1University of Cambridge Department of Chemistry Lensfield Road Cambridge CB2 1EW, UK. j.l.bolliger@gmail.com.
Abstract:
Chiral bis(diimine) ligands (derived from chiral enantiopure diamines and 2-formylpyridine) enantioselectively self-assemble with an iron (II) salt to either the tetrahedral cage molecule ΔΔΔΔ-[Fe4L6](8+) or its enantiomer, ΛΛΛΛ-[Fe4L6](8+). These versatile water-soluble capsules are capable of binding a wide range of organic guests in their large hydrophobic cavities. Among these guests is the neurotoxic insecticide dichlorvos, for which the ΔΔΔΔ-[Fe4L6](8+) coordination capsule serves as a competent supramolecular catalyst for its hydrolysis.
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