Proteomics and proteogenomics approaches for oral diseases

Area of Science:

• Nanomedicine
• Biotechnology
• Oral Health

Background:

• Advancements in biocompatible materials and nanogenomics/nanoproteomics are driving nanodentistry.
• Classical dentistry is evolving towards predictive, preventive, personalized, and participatory models.
• Global oral pathologies necessitate ethical considerations for universal oral health access.

Purpose of the Study:

• To review bioinformatics, nanogenomics, and nanoproteomics in contemporary nanodentistry.
• To emphasize the need for an integrated proteogenomics approach.
• To discuss clinical and translational implications and future perspectives.

Main Methods:

• Review of current literature on nanobiotechnologies in dentistry.
• Focus on bioinformatics, nanogenomics, and nanoproteomics.
• Analysis of proteogenomics integration for clinical applications.

Main Results:

• Nanobiotechnologies offer significant potential for improving global oral health.
• Integration of nanogenomics and nanoproteomics enables personalized dental treatments.
• Proteogenomics presents a promising avenue for future nanodentistry research and application.

Conclusions:

• Nanodentistry, powered by nanobiotechnologies, is crucial for advancing global oral health.
• An integrated proteogenomics approach is essential for the future of personalized and preventive dentistry.
• Continued research and development in nanodentistry promise significant clinical and translational benefits.