Levetiracetam-induced acute psychosis in a child

Area of Science:

• Neurology
• Pediatric Neurology
• Pharmacology

Background:

• Levetiracetam is a widely prescribed broad-spectrum antiepileptic medication.
• It is generally well-tolerated for managing partial and generalized seizures.
• Limited reports exist on levetiracetam-induced psychosis in pediatric populations.

Observation:

• This case details a child experiencing acute psychosis.
• The psychosis was directly linked to the initiation or dosage of levetiracetam.
• No other contributing factors were identified as the primary cause.

Findings:

• Levetiracetam can induce acute psychosis as an adverse effect in children.
• This highlights a potential, albeit rare, neuropsychiatric complication.
• The temporal relationship between levetiracetam use and psychotic symptoms was evident.

Implications:

• Clinicians should be aware of the potential for levetiracetam-induced psychosis in children.
• Close monitoring for psychiatric adverse effects is crucial in pediatric patients on levetiracetam.
• Early recognition and management can mitigate serious outcomes of drug-induced psychosis.