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Cilnidipine induced ankle edema.

Vishal R Annil1, Annil Mahajan2, Vivek Mahajan1

  • 1Department of Pharmacology and Therapeutic, Government Medical College, Jammu, Jammu and Kashmir, India.

Indian Journal of Pharmacology
|July 3, 2014
PubMed
Summary

Cilnidipine, a new hypertension drug, is generally not expected to cause ankle swelling. However, this report details a rare case of cilnidipine-induced ankle edema in a patient.

Keywords:
Adverse drug reactionsankle edemacalcium channel blockercilnidipine

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Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Cilnidipine is a fourth-generation dihydropyridine calcium channel blocker.
  • It is indicated for essential hypertension treatment.
  • Unlike amlodipine, cilnidipine is not typically associated with ankle edema.

Observation:

  • A patient developed ankle edema.
  • The edema was potentially linked to cilnidipine use.

Findings:

  • This case report documents cilnidipine-induced ankle edema.
  • This adverse effect is uncommon but possible.

Implications:

  • Cilnidipine may cause ankle edema, contrary to expectations.
  • Further investigation into this adverse effect is warranted.
  • This finding is crucial for managing hypertension patients.