Related Experiment Video
Updated: Apr 27, 2026

In vivo 19F MRI for Cell Tracking
Published on: November 25, 2013
Double-tuned radiofrequency coil for (19)F and (1)H imaging
Yosuke Otake1, Yoshihisa Soutome, Koji Hirata
1Central Research Laboratory, Hitachi, Ltd.
Abstract:
We developed a double-tuned radiofrequency (RF) coil using a novel circuit method to double tune for fluorine-19 (19F) and 1H magnetic resonance imaging, whose frequencies are very close to each other. The RF coil consists of 3 parallel-connected series inductor capacitor circuits. A computer simulation for our double-tuned RF coil with a phantom demonstrated that the coil has tuned resonant frequency and high sensitivity for both 19F and 1H. Drug distribution was visualized at 7 tesla using this RF coil and a rat administered perfluoro 15-crown-5-ether emulsion. The double-tune RF coil we developed may be a powerful tool for 19F and 1H imaging.
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