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Updated: Apr 27, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Dynamic CT perfusion imaging of the myocardium using a wide-detector scanner: a semiquantitative analysis in an
Daniela Muenzel1, Peter B Noël1, Bettina M Gramer1
1Department of Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 München, Germany.
Background:
Functional assessment of myocardial perfusion in computed tomography (CT) is a challenge.
Objective:
To evaluate CT dynamic myocardial perfusion imaging (MPI) using a wide-detector scanner.
Methods:
Time to peak (TTP), peak enhancement (PE), upslope (US), and the area under the curve (AUC) were calculated in 12 pigs (256-slice multidetector CT scanner).
Results:
The entire myocardium was covered by the scan volume. TTP was increased, and PE, US, and AUC were decreased in poststenotic myocardium.
Conclusion:
CT MPI with complete coverage of the myocardium is feasible, providing evaluation of the physiological significance of coronary artery stenosis.
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