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Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder
Published on: May 23, 2020
Neural control of lower urinary tract and targets for pharmacological therapy
Maria Augusta T Bortolini1, Andreisa P M Bilhar, Rodrigo A Castro
1Sector of Urogynecology and Vaginal Surgery, Department of Gynecology, Federal University of São Paulo, Rua Rodolfo Belz, 220/42A, São Paulo, 05639-010, SP, Brazil, maria.augusta@gmail.com.
Abstract:
Studies on the physiology and pharmacology of the lower urinary tract have brought new information and concepts about the complex neural control of micturition. There are many mechanisms, some proven and others not yet completely understood, in which pharmacological agents may act facilitating the filling, storage, and emptying of the bladder. This review describes the peripheral innervation and the main pathways involved in lower urinary tract control. It also presents potential targets for the treatment of voiding dysfunctions.
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