Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of Hemostasis01:24

Disorders of Hemostasis

2.7K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.7K
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

413
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
413
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

880
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
880
Introduction to Hemostasis01:05

Introduction to Hemostasis

13.9K
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
13.9K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

482
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
482
Blood Transfusion01:15

Blood Transfusion

3.0K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to 'Lack of factor VIII detection in humans and dogs with an intron 22 inversion challenges hypothesis regarding inhibitor risk' [Journal of Thrombosis and Haemostasis. Volume 22, Issue 12, December 2024, Pages 3415-3430].

Journal of thrombosis and haemostasis : JTH·2026
Same author

Joint tissue plasticity in hemophilia: insights from the Joint Activity and Damage Exam ultrasound protocol.

Research and practice in thrombosis and haemostasis·2026
Same author

Early Detection of Post-Traumatic Heterotopic Ossification in Bleeding Disorders Using Ultrasound: A Multi-Center Case Series.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2025
Same author

Efficacy and safety of marstacimab prophylaxis in hemophilia A/B with inhibitors: results from the phase 3 BASIS trial.

Blood·2025
Same author

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease.

Haemophilia : the official journal of the World Federation of Hemophilia·2024
Same author

International Society on Thrombosis and Haemostasis Clinical Practice Guideline for Treatment of Congenital Haemophilia-A Critical Appraisal.

Haemophilia : the official journal of the World Federation of Hemophilia·2024

Related Experiment Video

Updated: Apr 27, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K

Identification and basic management of bleeding disorders in adults.

Rebecca Kruse-Jarres1, Tammuella C Singleton2, Cindy A Leissinger2

  • 1From the Department of Medicine (RKJ, CAL), and the Department of Pediatrics (TCS), Tulane University School of Medicine, New Orleans, Louisiana. rkruseja@tulane.edu.

Journal of the American Board of Family Medicine : JABFM
|July 9, 2014
PubMed
Summary

Diagnosing bleeding disorders in adults requires careful evaluation of symptoms and lab results. Prompt identification and proper management are key to preventing complications and ensuring appropriate treatment.

Keywords:
Blood Coagulation DisordersBlood Platelet DisordersCoagulation Protein DisordersPartial Thromboplastin TimeProthrombin Time

More Related Videos

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
08:13

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

7.0K
A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

16.3K

Related Experiment Videos

Last Updated: Apr 27, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K
Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
08:13

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

7.0K
A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

16.3K

Area of Science:

  • Hematology
  • Internal Medicine

Background:

  • Adults may present with bleeding symptoms or incidental lab abnormalities.
  • Diagnosing underlying bleeding disorders can be challenging.

Purpose of the Study:

  • To review the diagnostic approach for bleeding disorders in adults.
  • To outline preventive care and hemostatic management strategies.

Main Methods:

  • Thorough patient history and physical examination.
  • Systematic evaluation of hematologic laboratory abnormalities.
  • Consideration of bleeding phenotype and procedural risk.

Main Results:

  • Specific lab abnormalities can guide investigation of hemostatic components.
  • Clinical presentation is crucial for identifying pathologic bleeding.
  • Understanding pathophysiology ensures appropriate treatment and avoids contraindications.

Conclusions:

  • A structured diagnostic approach is essential for adults with potential bleeding disorders.
  • Hematologist consultation is valuable, especially for rare or unexplained cases.
  • Effective management relies on accurate diagnosis and tailored care.