Related Experiment Video
Updated: Apr 27, 2026

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Uniportal Full Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
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Posterior surgery in high-grade spondylolisthesis.
R Lengert1, Y P Charles1, A Walter1
1Service de Chirurgie du Rachis, Hôpitaux Universitaires de Strasbourg, Fédération de Médecine Translationnelle (FMTS), Université de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France.
Summary
Posterior L4-S1 fusion better controlled L5-S1 lordosis reduction than L5-S1 fusion in high-grade spondylolisthesis. The lever-arm system effectively reduced slippage, with stable spinopelvic balance post-surgery.
Area of Science:
- Spine surgery
- Orthopedic surgery
- Radiology
Background:
- High-grade L5-S1 spondylolisthesis disrupts sagittal spinopelvic balance, potentially causing low back pain and neurological deficits.
- Surgical intervention is necessary to correct slippage and restore spinal alignment.
Purpose of the Study:
- To compare the effectiveness of L4-S1 versus L5-S1 posterior fusion using a lever-arm system for spondylolisthesis reduction and maintenance.
- To assess changes in spinopelvic parameters and segmental lordosis over time.
Main Methods:
- Retrospective analysis of 40 patients with symptomatic high-grade spondylolisthesis, with 34 having complete radiological data.
- Comparison of L4-S1 (n=25) versus L5-S1 (n=9) instrumentation groups.
- Evaluation of spinopelvic parameters, slipping index, and lordosis evolution over a mean 5.4-year follow-up.
Main Results:
- The lever-arm system significantly reduced the Taillard spondylolisthesis index (64% to 37%).
- L4-S1 fusion demonstrated superior long-term maintenance of L5-S1 lordosis reduction compared to L5-S1 fusion (P=0.006).
- Overall sagittal spinopelvic balance and L1-S1 lordosis remained largely unchanged post-operatively.
Conclusions:
- The lever-arm system effectively reduces spondylolisthesis and corrects slippage with stable postoperative spinopelvic balance.
- Posterior L4-S1 fusion offers better long-term control of L5-S1 lordosis reduction compared to L5-S1 fusion.
- This study highlights the benefits of longer fusion constructs for maintaining reduction in high-grade spondylolisthesis.
Keywords:
High-grade spondylolisthesisInstrumentation lengthLumbosacral fusionSagittal balanceSegmental lordosisSlippage parameters
