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Mortality due to Chagas disease in Brazil according to a specific cause

Aglaêr Alves da Nóbrega, Wildo Navegantes de Araújo, Ana Maria Nogales Vasconcelos

    The American Journal of Tropical Medicine and Hygiene
    |July 9, 2014
    PubMed

    Insights

    Chagas disease mortality decreased significantly in Brazil from 2000 to 2010, primarily affecting older males due to cardiac issues. However, digestive tract involvement mortality rose, necessitating continued public health surveillance.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Epidemiology

    Background:

    • Chagas disease (CD) remains a significant public health concern a century after its discovery.
    • Understanding mortality trends is crucial for effective disease management and control strategies.

    Purpose of the Study:

    • To analyze Chagas disease mortality in Brazil between 2000 and 2010.
    • To identify trends in mortality based on underlying cause, demographics, and geographic region.

    Main Methods:

    • Analysis of mortality data from Brazil for the period 2000-2010.
    • Standardized mortality rates were calculated and stratified by cause, year, gender, age, and region.

    Main Results:

    • Overall standardized mortality rate for Chagas disease decreased by 32.4% from 2000 (3.4%) to 2010 (2.3%).
    • The majority of deaths (85.9%) occurred in males over 60 years old, predominantly due to cardiac complications.
    • While cardiac mortality decreased nationwide, it increased in the North region. Digestive tract involvement mortality rose across all regions.

    Conclusions:

    • Despite a general decline in Chagas disease mortality, particularly cardiac-related deaths, the increase in digestive form mortality and regional variations highlight the need for ongoing surveillance.
    • Continued public health interventions and surveillance are essential to manage Chagas disease in Brazil, even with controlled transmission routes.

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