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Meningoencephalitis in a dog due to Trichosporon montevideense

L K Bryan1, B F Porter1, B L Wickes2

  • 1Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, USA.

Journal of Comparative Pathology
|July 10, 2014
PubMed

Insights

A dog was diagnosed with meningoencephalitis caused by Trichosporon montevideense, a rare fungal infection affecting the brain. This case highlights the importance of considering fungal infections in canine neurological disease.

Area of Science:

  • Veterinary Neurology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal meningoencephalitis is an uncommon but serious condition in dogs.
  • Trichosporon species are known human pathogens but rarely reported in veterinary medicine.

Observation:

  • A 4-year-old dog presented with rapidly progressing neurological signs, leading to a comatose state.
  • Post-mortem examination revealed pyogranulomatous inflammation in the cerebrum with fungal hyphae.

Findings:

  • Culture and sequence analysis identified Trichosporon montevideense in the dog's brain.
  • DNA in-situ hybridization confirmed the fungal meningoencephalitis diagnosis.

Implications:

  • This is the first documented case of Trichosporon-associated meningoencephalitis in a canine.
  • This finding expands the known spectrum of fungal pathogens causing neurological disease in dogs.
  • Further research may be warranted to understand the prevalence and pathogenesis of Trichosporon infections in animals.
Keywords:
Trichosporon montevideensedogin-situ hybridizationmeningoencephalitis

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