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A Web Tool for Generating High Quality Machine-readable Biological Pathways
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Processing biological literature with customizable Web services supporting interoperable formats.

Rafal Rak1, Riza Theresa Batista-Navarro2, Jacob Carter3

  • 1National Centre for Text Mining, School of Computer Science, University of Manchester, M1 7DN, UK and Department of Computer Science, University of the Philippines Diliman, Philippines 1101 rafal.rak@manchester.ac.uk.

Database : the Journal of Biological Databases and Curation
|July 10, 2014
PubMed
Summary
This summary is machine-generated.

Web services enhance scientific literature processing. Argo workbench analytics for biochemical concepts in BioC format achieved top scores in the BioCreative challenge, showcasing interoperability.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Text Mining

Background:

  • Web services are increasingly used for scientific literature processing.
  • Interoperability of Web services relies on suitable data exchange formats.
  • The biological domain requires domain-specific and generic representations.

Purpose of the Study:

  • To evaluate four interoperability formats (BioC, BioNLP, XMI, RDF) for biological Web services.
  • To demonstrate customizable Web service creation using the Argo text-mining workbench.
  • To assess the performance of automated analytics within Web services.

Main Methods:

  • Utilized the Argo Web-based text-mining workbench for customizable Web service creation.
  • Configured Web services to accept and produce various input/output data interchange formats.
  • Evaluated four interoperability formats: BioC, BioNLP, XMI, and RDF.
  • Participated in the BioCreative IV challenge to quantitatively evaluate automated analytics.

Main Results:

  • Achieved the highest combined scores among 10 teams in the BioCreative IV challenge for biochemical concept recognition.
  • Demonstrated 2-fold customization of Web services: pipeline construction and data format configuration.
  • Provided qualitative evaluation of the four considered interoperability formats.

Conclusions:

  • The Argo workbench facilitates the creation and deployment of customizable Web services for biological text mining.
  • BioC collections and associated analytics show high performance and interoperability for biochemical concept recognition.
  • The evaluated formats offer different strengths for domain-specific and generic scientific data exchange.