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Published on: November 19, 2018
Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome
Kaiguang Yang1, Jianxi Liu, Senwu Li
1CAS Key Lab of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. lihuazhang@dicp.ac.cn.
Abstract:
Polymer self-assembly was developed as an epitope imprinting strategy involving facile processes and high recognition site density. As a model, transferrin epitope imprinted polyethersulfone (PES) beads were successfully fabricated using this technique. The imprinted beads demonstrated excellent selectivity toward the transferrin epitope and transferrin even in the real sample.

