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Updated: Apr 27, 2026

High-resolution Confocal Imaging of the Blood-brain Barrier: Imaging, 3D Reconstruction, and Quantification of Transcytosis
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A new micro-computed tomography-based high-resolution blood-brain barrier imaging technique to study ischemic stroke

Jin-Yong Park1, Su-Kyoung Lee1, Jeong-Yeon Kim1

  • 1From the Molecular Imaging and Neurovascular Research (MINER) Laboratory, Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea (J.-Y.P., S.-K.L., J.-Y.K., K.-H.J., D.-E.K.); and Departments of Radiology and Experimental Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston (D.S.).

Stroke
|July 12, 2014
PubMed
Summary

A new micro-computed tomography (mCT) technique using intra-arterial iopromide effectively visualizes blood-brain barrier (BBB) dysfunction after stroke in mice. This method offers high resolution and sensitivity for dynamic BBB assessment in vivo.

Keywords:
blood-brain barrierinfusion, intra-arterialiopromideischemic strokemicro–CT

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