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Mitomycin-C for mucous membrane overgrowth in OOKP eyes
Venkata S Avadhanam1, Jim Herold, Simon Thorp
1*Sussex Eye Hospital, Brighton, United Kingdom; †Brighton and Sussex Medical School, Brighton, United Kingdom; ‡Royal Sussex County Hospital, Brighton, United Kingdom; and §Tongdean Eye Clinic, Hove, United Kingdom.
Purpose:
The aim of this study was to report the use of mitomycin-C (MMC) in the treatment of mucous membrane overgrowth in eyes with osteo-odonto-keratoprosthesis (OOKP).
Methods:
Records of 4 cases with mucous membrane overgrowth after stage 2 OOKP surgery were reviewed.
Results:
All the patients had undergone a mucous membrane trimming procedure followed by MMC application. None of the patients had any episode of recurrence of the mucous membrane overgrowth after a single application of MMC in the follow-up period that ranged from 1 to 11 years.
Conclusions:
MMC can successfully arrest mucous membrane overgrowth in OOKP-implanted eyes including refractory cases.
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