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Updated: Apr 27, 2026

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
Published on: March 17, 2023
[Hypotheses for the genesis of cancer: a historical perspective]
1Centre Cavaillès, République des savoirs, USR 3608, École normale supérieure, 46, rue d'Ulm, 75005 Paris, France.
Abstract:
The explanation of cancer has always been tightly related to the state of knowledge in biology, and its transformations. The present situation is not different. New techniques, such as deep sequencing, are rapidly moving our vision of cancer in an impredictable way. Systems biology, epigenetics, and the study of stem cells are generating new hypotheses on cancer and its evolution. New roles for aleatory events in the genesis of cancer have been proposed. In the traditional opposition between holism and reductionism, organisms and molecules, an intermediary level, the cancer cell, seems to be the most appropriate to study oncogenesis.
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